Search results for "Lithium amide"

showing 6 items of 6 documents

ChemInform Abstract: Enantioselective α-Alkylation of Unsaturated Carboxylic Acids Using a Chiral Lithium Amide.

2010

Abstract The regio- and stereochemistry of the alkylation of dienediolates from unsaturated carboxylic acids with benzylic halides, which often results in mixtures of isomers, can be controlled by means of changes in the lithium amide, allowing the α-regioisomer to be obtained as the major diastereoisomer. In addition, when chiral amines are used, moderate enantiomeric excesses can be attained.

Lithium amideorganic chemicalsfungiDiastereomerEnantioselective synthesisfood and beveragesHalideGeneral MedicineAlkylationchemistry.chemical_compoundchemistrypolycyclic compoundsOrganic chemistryheterocyclic compoundsEnantiomerChemInform
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Early transition metal derivatives stabilised by the phenylenediamido 1,2-C6H4(NCH2tBu)2 ligand: Synthesis, characterisation and reactivity studies: …

2009

Abstract Li 2 [1,2-C 6 H 4 (NCH 2 t Bu) 2 ] reacts with one equiv of [TiCl 4 (THF) 2 ] in refluxing toluene to give the chelate compound [Ti{1,2-C 6 H 4 (NCH 2 t Bu) 2 }Cl 2 (THF)] ( 1 ), isolated as a black product, while the reaction of the dilithio diamido salt with one equiv of [ZrCl 4 (THF) 2 ] in refluxing toluene affords the dinuclear zirconium derivative [Zr{1,2-C 6 H 4 (NCH 2 t Bu) 2 }Cl(THF)(μ-Cl)] 2 ( 2 ), obtained as an orange solid. Treatment of the dilithio diamido salt with TaCl 5 in a 2:1 molar ratio in toluene yields [Ta{1,2-C 6 H 4 (NCH 2 t Bu) 2 } 2 Cl] ( 3 ) as a red product. The reaction of 1,2-C 6 H 4 (NHCH 2 t Bu) 2 with [Zr(NMe 2 ) 4 ] in toluene at room temperature …

Lithium amideLigandStereochemistryMethylaluminoxaneCrystal structureMetallacycleMedicinal chemistryInorganic Chemistrychemistry.chemical_compoundchemistryPhenyleneDiamineMaterials ChemistryLewis acids and basesPhysical and Theoretical ChemistryPolyhedron
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Syntheses and reactivity of aminobis(diorganylamino)phosphanes

1996

Aminobis(diorganylamino)phosphanes (R2N)2PNH2 (R = iPr, c-Hex, Ph) (2a–c), were obtained by treatment of the corresponding chlorobis(diorganylamino)phosphanes 1a–c with lithium amide in liquid ammonia. The transition metal phosphane complex (R2N)2(H2N)PNi(CO)3 (3) was prepared by reaction of 2a with tetracarbonylnickel. N-Complexation of 2a with trimethylalane affords the iminophosphorane-alane adduct (R2N)2HP=N(H)AlMe3 (4) by 1,2-H shift from the nitrogen to the phosphorus atom. The corresponding reaction with aluminium trichloride leads to the formation of the salt [(R2N)2HP=N(H)]2AlC12+[AlC14]− (5), in which two iminophosphorane moieties are linked by an AlCl2 bridge. Lithiation of 2a an…

Inorganic Chemistrychemistry.chemical_compoundLithium amideNucleophilechemistryTransition metalInorganic chemistryTitanocene dichlorideReactivity (chemistry)TautomerIsomerizationMedicinal chemistryAdduct
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Atomic layer deposition of lithium containing thin films

2009

Five different lithium containing compounds, all representing different chemical systems, were studied in order to deposit lithium containing films by atomic layer deposition ALD. The studied compounds were a lithium β-diketonate Li(thd) (thd = 2,2,6,6-tetramethyl-3,5-heptanedionate), a lithium alkoxide LiOtBu (OtBu = tert-butoxide), a lithium cyclopentadienyl LiCp (Cp = cyclopentadienyl), a lithium alkyl n-butyllithium, and a lithium amide lithium dicyclohexylamide. Films containing lithium carbonate (Li2CO3) were obtained from alternate pulsing of Li(thd) and ozone in a temperature range of 185–300 °C. The film composition was analyzed by time-of-flight elastic recoil detection analysis (…

Lithium amideChemistryInorganic chemistryLithium carbonatechemistry.chemical_elementGeneral ChemistryAtomic layer depositionchemistry.chemical_compoundLanthanum oxideAlkoxideMaterials ChemistryLithiumLithium oxideThin filmJournal of Materials Chemistry
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Enantioselective α-alkylation of unsaturated carboxylic acids using a chiral lithium amide

2001

Abstract The regio- and stereochemistry of the alkylation of dienediolates from unsaturated carboxylic acids with benzylic halides, which often results in mixtures of isomers, can be controlled by means of changes in the lithium amide, allowing the α-regioisomer to be obtained as the major diastereoisomer. In addition, when chiral amines are used, moderate enantiomeric excesses can be attained.

Lithium amideChemistryorganic chemicalsfungiOrganic ChemistryEnantioselective synthesisDiastereomerfood and beveragesHalideAlkylationCatalysisInorganic Chemistrychemistry.chemical_compoundpolycyclic compoundsOrganic chemistryheterocyclic compoundsPhysical and Theoretical ChemistryEnantiomerTetrahedron: Asymmetry
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Linked Benzylamido-Cyclopentadienyl Ligands: Synthesis and Characterization of Alkyl Titanium Complexes

1997

Titanium complexes of the general type Ti(η5:η1-C5H4Si-Me2NCH2C6H3X2-2,5)Cl2 (XH, F), containing a linked benzylamido-cyclopentadienyl ligand, were prepared by reaction of Ti(η5-C5H4SiMe2Cl)Cl3 with lithium amide Li(NHCH2C6H3X2-2,5). A single-crystal X-ray structural analysis of Ti(η5: η1-C5H4SiME2NCH2C6H3F2-2,5)Cl2 revealed a conformation in the solid state in which the aryl ring is turned away from the metal center. Ti(η5:η1-C5H4SiMe2NCH2C6H5)Cl2 can be alkylated with a variety of reagents to form extremely sensitive complexes of the type Ti(η5-C5H4SiMe,2NCH2C6H5)R2 (RMe, CH2 C6H5, CH2SiME3, CH2CMe2C6H5). Reaction of Li2[C5Me4SiMe2NCH2C6H5] with TiCl3(THF)3 gave Ti(η5: η1-C5Me4SiMe2NCH2C6…

chemistry.chemical_classificationLithium amideLigandStereochemistryArylchemistry.chemical_elementAlkylationInorganic Chemistrychemistry.chemical_compoundCrystallographychemistryCyclopentadienyl complexLewis acids and basesAlkylTitaniumChemische Berichte
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